Scientific program

07:30

08:00 – 09:30

• Optimizing advice and approaches for oocyte preservation – Paola Vigano (Italy)
• Elective uterine preservation: a new concept – Christian Becker (UK)
• Not just a womb: the role of non-pregnant uterus as an endocrine organ – Ayman Al-Hendy (USA)
• Best strategy for adenomyosis-related infertility – Charles Chapron (France)

09:00 – 09:30

Free Communications 1

• Deep endometriosis surgery may increase the risk of adverse obstetric events: a retrospective cohort study – Yannick Hurni (Spain)
• Correlation Between Symptoms, Ultrasonography and Office Hysteroscopy in Cesarean Scar Defect – Tamer A Hosny (Egypt)
• Releasing the frozen pelvis in advanced endometriosis: standardised surgical steps (SUOP-PC) – Sachin Naiknaware (India)

Free Communications 2

• Efficacy and safety of elagolix in Chinese patients with moderate or severe endometriosis-associated pain: a multicenter, randomized, double‑blind, placebo‑controlled Phase 3 Trial – Huang Yan (China)
• Concomitant right-sided bowel resection with left colorectal surgery for deep endometriosis: does it increase major morbidity? Evidence from 1,075 patients – Adrien Crestani (France)
• From transcriptomics to real-world evidence: electronic medical records analysis supports simvastatin as a potential therapy for endometriosis – Tomiko Oskotsky (United States)

Free Communications 3

• Long-term impact of colorectal surgery for deep endometriosis on bladder function: a 2- and 5-year risk-based analysis – Elena Giubegeanu (Romania)
• Comparative analysis of AI and human annotators in the segmentation of pelvic organs and endometriosis on transvaginal ultrasound – Julian Metzler (Switzerland)
• IL-33 Activates ILC2s via JAK3/STAT6 to Promote Pro-angiogenic and Pro-invasive Programs in Endometrial Stromal Cells in Endometriosis – Zhimin Lu (China)

Free Communications 4

• LaLaSTADR (Laparoscopic laser shaving and TransAnal Discoid Resection)- A retrospective study over 200 women with deep infiltrating endometriosis in Belgium – Ghyssens Mercedes (Belgium)
• Endometriosis is associated with regionalized impairment of digestive functions – Michel Neunlist (France)
• Detection and quantification of free pelvic fluid by transvaginal ultrasound as a proxy for retrograde menstruation: a cohort study – Noemi Salmeri (Italy)

Free Communications 5

• Polypoid endometrioma mimicking malignant transformation: case report and systematic review – Guillaume Parpex (France)
• Evolution of endometrioma volume after medical treatment: comparative analysis and profile of patients treated with Ryeqo –Emanuela Spagnolo (Spain)
• Research on the application of circulating endometrial cells (CECS) in the clinical diagnosis of endometriosis – Ze Zhang (China)

Free Communications 6

• Patient-specific cellular invasion and remodeling in endometriosis: toward a predictive tool – Isabelle Chickanosky (United States)
• Upregulation of DEK expression in uterine myomas and cervical cancer as a potential prognostic factors – Anastasia Tsigkou (China)
• Clinical implications of uterine fibroids on perinatal care – Monika Kopec (Poland)

Free Communications 7

• The coagulation status in symptomatic adenomyosis patients with adenomyomectomy – Minhong Shen (China)
• High intensity focused ultrasound treatment and long-term management of adenomyosis combined with infertility – Wang Sixue (China)
• Analysis of a case of successful twin pregnancy with refractory intrinsic adenomyosis – Xinmei Zhang (China)

Free Communications 8

– Efficacy and safety of sclerotherapy for the management of endometrioma in adolescent and young unmarried girls – Rashida Begum (Bangladesh)
– Laparoscopic Uterine Artery Occlusion in Conservative Surgery For Uterus – Qiqi Long (China)
– Perioperative Safety in Endometriosis Surgery: Outcomes from a Strategy-Based Single-Center Experience – Hanako Kaseki (Japan)

10:00 – 12:30

Free Communications 9

• Beyond pain: the intriguing cases of hemorrhagic ascites in endometriosis and its clinical implications –  Elham Askari (Iran)
• The strength in nature – therapeutic potential of bee product Propolis in Endometriosis. Scientific Evidences – Monika Kopec (Poland)
• Fertility after colorectal surgery for endometriosis comparing conventional laparoscopy and robotic assisted laparoscopy. Should all patients benefit from robotic approach? Eric De Labrouhe (France)
• Epithelial and mesenchymal tissue phenotypes and cell markers coexist in endometriotic lesions – Fernando Reis (Brazil)
• Multidisciplinary approach to laparoscopic resection of abdominal wall endometriosis and mesh repair utilizing intraoperative ultrasound and transabdominal needle placement – Menghui Li (China)
• Knowledge, attitudes, beliefs, and practices of general practitioners regarding endometriosis – Sarah Gaston-Dreyfus (France)
• Revolutionising endometriosis diagnosis: a non-invasive approach using menstrual blood – Peter Oppelt (Austria)
• Rapidity of onset of dysmenorrhoea and non-menstrual pelvic pain reduction with Linzagolix in women with endometriosis-associated pain: a post-hoc analysis of the EDELWEISS trials – Christian Becker (United Kingdom)
• Bone mineral density outcomes in women aged <35 years and ≥35 years with endometriosis treated with Linzagolix: a post-hoc analysis of the EDELWEISS trials – Lucy Whitaker (United Kingdom)
• Early septic complications after colorectal resection with natural orifice specimen extraction for endometriosis: predictive value of C-reactive protein monitoring – Pierrick Godin (Belgium)
• The decreased expression of ECM1 activates the TGF-β pathway in endometriotic stromal cells, leading to fibrosis – Xinyi Zhang (China)
• The Endogenesi App: improving quality of life and awareness of endometriosis patients using personalized web app with indications about non pharmacological support and lifestyle changes – Luigi Fasolino (Italy)
• Preoperative CA125 as an independent predictor of severe pelvic adhesions in endometriosis: a retrospective study – Lee Seungho (Republic of Korea)

Free Communications 10

• Ethnic Differences in Endometriosis Diagnosis Among South Asian and Chinese Patients – Kevin Kuan (Canada)
• Should frozen embryo transfer be preferred over fresh transfer across endometriosis phenotypes? A meta-regression and network meta-analysis – Shelly Franciska Suharja (Indonesia)
• Dual ultrasound combination in assessing rectal Endometriosis: a pilot study – Hailan Yan (China)
• Improvement in urinary symptoms and quality of life after partial bladder excision for endometriosis – Clara Rigori (France)
• Identification of candidate microRNA biomarkers of endometriosis in different bodily fluids – Jinghua Shi (China)
• Combined serum miR-34a-5p and miR-200a-3p as non-invasive biomarker panel for peritoneal endometriosis especially in young nonsmokers due to shared inflammatory pathways – Katharina Proestling (Austria)
• Characterizing the endometriosis patient journey in a German cohort: experiences from the LIDEA Registry – Pauline De Corte (Germany)
• Successful immunotherapy/targeted therapy for rapidly progressive endometriosis-associated ovarian squamous cell carcinoma: a case report – Zhijun Hu (China)
• Case report and literature review of obstructive reproductive tract malformation and complex endometriosis – Ping Xu (China)
• Long-term outcomes of surgical management for ureteral endometriosis with hydroureteronephrosis: a retrospective study –  Tang Xinyue (China)
• Ultrasound endometriosis findings in adolescents: a comprehensive photographic overview of 3 years – Ilaria Mazzera (Italy)
• Does endometriosis alter early pregnancy steroidogenesis? Evidence from a matched case–control study – Giorgia Di Stefano (Italy)

Free Communications 11

• Therapeutic efficacy and mechanisms of dydrogesterone in the mouse model of endometriosis – Xinmei Zhang (China)
• Assessing the impact of endometriosis on pregnancy outcomes: a two-sample Mendelian randomization study – Jonas Vibert (Switzerland)
• Application of pedicled myocutaneous flap combined with vacuum sealing drainage technique in massive abdominal wall endometriosis – Zhu Libo (China)
• Single-cell and spatial transcriptomic profiling revealed niche interactions of endometriotic lesions – Gu Zhiyue (China)
• Protein biomarkers in cervical fluids for endometriosis diagnosis – Raquel Delgado-Gil (Spain)
• Spatial transcriptomic profiling revealed niche interactions sustaining the growth of ovarian endometriosis lesions – Wang Sixue (China)
• Implementing the IDEA protocol: early experience from the establishment of the Alexandria University endometriosis unit – Ahmed Khalifa (Egypt)
• Extrapelvic endometriosis: a retrospective case series highlighting diagnostic and therapeutic challenges – Igor Prissiajnyi (Spain)
• Inter- and intra-patient heterogeneity in ovarian endometriosis: implications for molecular research and personalized medicine – Carina Masferrer-Ferragutcasas (Spain)
• The incidence of endometrioma coexisting with other ovarian cysts – Chenyu Zhang (China)

Free Communications 12

• Comparative effectiveness of dienogest, ethinylestradiol/dienogest and desogestrel on ovarian endometrioma volume: a long-term sonographic study – Maria Cristina Sangiovanni (Italy)
• Extracellular vesicle–based biomarker discovery in endometriosis: a translational analysis from cell culture to plasma – Jasmina Hoffe (Germany)
• Persistent and therapy-refractory endometriosis decades after total hysterectomy and bilateral adnexectomy – a 50-year case report – Benedikt Schäfgen (Germany)
• Whole-genome methylation profiling of menstrual stem cells identifies novel biomarkers for endometriosis – Cristina Fernandez-Molina (France)
• Effects of changes in fat metabolism by particulate matter on endometrium and infertility – Jung Gee Soo (Republic of Korea)
• Clinical characteristics and risk factors of ureteral endometriosis in patients with deep infiltrating endometriosis: a retrospective cohort study – Zhijun Hu (China)
• Discovery of peritoneal endometriosis blood biomarkers through whole-blood transcriptomics and machine learning approaches – Maja Pusic Novak (Slovenia)
• Imaging of endometriotic and adenomyotic lesions after pregnancy – Anna Rosa Speciale (Italy)
• A novel endometriosis research model: a dual-color pseudo-menstrual mouse model for in vivo dynamic monitoring of circulating endometrial cells – Hou Chenyu (China)
• Prognostic factors for recurrence after radical excision of endometriosis – Joo-Won Park (Republic of Korea)
•C-reactive protein-triglyceride-glucose index as a potential diagnostic biomarker for endometriosis, a case-control study – Samaneh Rokhgireh (Iran)
• Ovario-protective effect of intra-ovarian injection of Platelet Rich Plasma (PRP) after laparoscopic cystectomy of ovarian endometrioma: a randomized control trial – Samaneh Rokhgireh (Iran)
• GnRH Antagonists for endometriosis treatment: experience in a tertiary referal center – Cardiel Ada (Spain)

Free Communications 13

• Clinical characteristics and long-term postoperative outcomes in patients with ovarian endometrioma without dysmenorrhea – Dai Yi (China)
• Early pregnancy sex steroid hormone patterns in singleton gestations among women with endometriosis compared with controls – Gianfranco Fornelli (Italy)
• Therapeutic challenges in a premenopausal breast cancer patient with severe endometriosis and hypersensitivity and intolerance to leuprolide acetate – Daniza Tinagan (Philippines)
• Clinical profile and management of hospitalized patients with acute endometriosis-related pelvic pain – Virginia Manzi (Italy)
• Vaginal deep endometriosis: clinical and ultrasound characteristics and association with other endometriotic localizations – Cristina Ros Cerro (Spain)
• Comparison between vaginal deep endometriosis and uterosacral ligament deep endometriosis without vaginal involvement: a case–control study – Cristina Ros Cerro (Spain)
• Safety and surgical outcomes of one-stage resection of anterior and posterior compartment deep endometriosis: final results from a multicentric study – Flavia Pagano (Switzerland)
• Real-world effectiveness and tolerability of relugolix–estradiol–norethisterone acetate (Ryeqo®) for chronic pelvic pain in women with endometriosis – Francesca Donders (Belgium)
• Association between uterine isthmus niche and lesion severity in cesarean scar–related subcutaneous endometriosis: a cross-sectional study in Indonesia – Irene Sinta Febriana (Indonesia)
• Menstruation-related functional impairments: a comparison between women with endometriosis and the general population – Clara Köhler (Germany)
• Pathogenesis of endometriosis : a prehistoric origin ? Gautier Chene (France)
• Protective stoma in bowel surgery for deep infiltrating endometriosis: does it improve postoperative outcomes ? Cloé Vaineau (Switzerland)
• Dysregulation of miR-124-3p, miR-150-5p, and miR-661 as a signature of implantation failure in women with deep endometriosis – Hajar Erraji (Morocco)
• Pain phenotypes in endometriosis and association with quality of life: a population-based study using latent class analysis – Sarah Maheux-Lacroix (Canada)

Free Communications 14

• Fertility-preserving push surgery for diffuse uterine leiomyomatosis: a 60-patient prospective series with three term live births – Xinfeng Qu (China)
• PUSH surgery for diffuse adenomyosis: distinct strategies and outcomes in internal vs external subtypes – Ruifang Wu (China)
• Predictors of difficult total hysterectomy in patients with adenomyosis – Bingrong Lian (China)
• Adenomyomectomy without post-operative medication for symptomatic adenomyosis: a three-year follow-up study – Xishi Liu (China)
• Anthropometric characteristics and incidence of uterine fibroids: results from the French E3N prospective cohort – Yveline Ansaldi (France)
• Reproductive outcome and fibroid recurrence after myomectomy: a retrospective study in a tertiary academic center in oman – Maryam Al Shukri (Oman)
• Estrogen receptor agonists fed neonatally differ in their effects on schwann cell dedifferentiation and their associated risk of adenomyosis in mice – Xi Wangxi (China)
• Adenomyosis in pregnancy: can ultrasound features predict obstretric and neonatal outcomes? – Claudia Morgani (Italy)
• Adenomyosis and live birth: what should we expect? – Claudia Morgani (Italy)
• Antenatal and delivery outcomes in twin pregnant women after uterine adenomyomectomy: summary of 5 cases – Jae Young Kwack (Republic of Korea)
• Cesarean delivery after adenomyomectomy and transabdominal cervico-isthmic cerclage (TCIC): a first and successful case report – Young Seo Sim (Republic of Korea)
• Dienogest slows but does not suppress uterine fibroid growth: a comparison with untreated controls – Deyu Zhang (China)
• Menstrual and reproductive factors and risk of uterine leiomyomata after age 40 in the E3N – Generations French Cohort – Sara Hachem (France)

Free Communications 15

• Long-term epigenetic changes in uterus induced by neonatal feeding of tamoxifen in female ICR mice – Yishan Chen (China)
• Differences in the proteomic profiles of the eutopic endometrium in patients with internal and external adenomyosis – Francisco Carmona (Spain)
• Ambulatory hysteroscopy optimizes the management of ultrasound-diagnosed submucosal fibroids: diagnostic accuracy and see-and-treat feasibility – Marta Miguez Medina (Spain)
• Diagnostic accuracy of the Myometrial Vascular Index (MVI): a semi-automated 2D Power Doppler biomarker for adenomyosis – Théo Lemouton (France)
• A dual-blockade protocol for women suffering from adenomyosis-related infertility: proposing a “3-Stratum Management Framework” for identifying beneficiaries and a “Visual Triad” of hysteroscopic findings for assessing readiness for Frozen Embryo Transfer – Nhut Luan Au (Vietnam)
• Integrative multi-omics characterization identifies molecular subtypes of adenomyosis associated with clinical phenotype and hormonal treatment response – Yuanmeng Liu (China)
• Adenomyosis and proliferative endometrial disorders – Francesco La Torre (Italy)
• Efficacy and tolerability of Linzagolix in patients with uterine fibroids – Milo Giani (Italy)
• Adenomyosis: should it be a warning sign for pelvic adhesions? An analysis by type, degree, and location toward the definition of soft markers for the evaluation of the pelvic peritoneum – Palumbo Mario (Italy)
• Clinical history of adolescent adenomyosis – Federico Toscano (Italy)
• Reproductive dysfunction in uterine fibroids: comparative analysis with other benign uterine pathologies – Zeynab Huseynova (Azerbaijan)
• Direct MUSA ultrasound features are more predictive of presence and severity of symptoms in diffuse adenomyosis: results from a French cross-sectional multicenter study – Téodor Grand (France)
• Unfolding fertility post-septolysis: long-term pregnancy outcomes and associated complications in a large cohort study – Elham Askary (Iran)

Free Communications 16

• Rectal endometriosis – Saeed Alborzi (Iran)
• Comparative efficacy of single vs. Double dose gnrh agonist for final oocyte maturation in endometriosis patients undergoing planed oocytes cryopreservation – Saeed Alborzi (Iran)
• Comparing 2D and 3D ultrasound in detection the sub-mucousal involvement in case of rectal endometriosis – Saeed Alborzi (Iran)
• New technique for restoring uterine cavity by resection of septum from fundus to cervical canal (retrograde septoplasty) – Tamer A Hosny (Egypt)
• Retained products of conception (RPOC): optimal treatment strategies with consideration for future fertility – Tomoko Nakamura (Japan)
• Is infertility a phenotype of accelerated aging? An epigenetic clock perspective – Letizia Li Piani (Italy)
• Clinical effectiveness of a multimodal diagnostic strategy including HPV E6Ee7 mRNA testing in the early detection of cervical pathologies – Nurana Ariz Hamidova (Azerbaijan)
• Recurrent pain after laparoscopic surgery for ovarian endometrioma: clinical features and long-term follow up – Wu Yushi (China)
• Targeting p300-mediated epigenetic regulation of pain in endometriosis using computational drug repurposing – Hajar Erraji (Morocco)
• Case study: multimodal physical therapy including TECAR radiofrequency for treatment of chronic pelvic pain in a patient after exploratory laparoscopy for suspected endometriosis – Melanie Carminati (United States)
• Vulvodynia: outcomes of a multidisciplinary approach – Angela Gallone (Italy)
• Altered pain modulation and pronociceptive profiles in women with endometriosis chronic pelvic pain – Lara Quintas-Marquès (Spain)

Free Communication 17 – Video Session

• Laparoscopic excision of ovarianendometrioma, deep infiltratingendometriosis and adenomyoma – Yingchen Wu (China)
• Ureteral identification during single-port laparoscopic salpingo-oophorectomy for ovarian endometrioma – Li Lan Ying (China)
• Lateral approach for vascular and neural decompression in parametrial endometriosis: laparoscopic video demonstration – Luccas Chagas (Brazil)
• Laparoscopic surgical management of a massive deep infiltrating endometriosis lesion in the uterosacral ligament – Guan Lin (China)
• Clinical outcome of endometriosis treatment protocol; radical excision and 3 cycles of postoperative GnRH agonist without long-term adjuvant hormonal therapy – Young Seo Sim (Republic of Korea)
• Time to conception after Laparoscopic myomectomy, prospective study of 300 patients – Shilpi Shukla (India)
• A case of repeat laparoscopy for treatment of deep endometriosis using ICG for intraoperative staining of ureters in patients after previous ureter reimplantation – Avishalom Sharon (Israel)
• Robotic approach to a giant myomatous uterus using the Da Vinci Xi System: optimization of port placement and instrument configuration – Juan Carlos Torrejon-Becerra (Spain)
• Robotic approach for retroperitoneal myomectomy in context of severe endometriosis – Kevin Kuan (Canada)
• Prophylactic ureteral suturing after ureterolysis in deep endometriosis: a conservative laparoscopic technique – Maria Cristina Sangiovanni (Italy)
• Laparoscopic abdominal cerclage at 15 weeks of gestation after trachelectomy: a step- by-step surgical video – Oriane Bernigaud (France)
• Posterior colpotomy for specimen retrieval during laparoscopic myomectomy: step by step technique – Jose Maria Puerta Sanabria (Spain)

10:00 – 12:30

Experts: Ursula Catena (Italy), Marcelo Ceccaroni (Italy), Vito Chiantera (Italy), Attilio di Spiezio (Italy), Harald Krentel (Germany), Abhishek Mangeshikar (India), Michael Mueller (Switzerland), Filipa Osorio (Portugal), Victoria Rey (Spain), Helena Van Kerrebroeck (Belgium), Brunella Zizolfi (Italy)

12:30 – 13:00

• Should we be afraid of hormonal treatments? Jonathan Douxfils (Belgium)

13:15 – 14:15

• Diagnostic Challenges and Unmet Needs in Endometriosis – Felice Petraglia (Italy)
• Scientific Validation of the Ziwig Endotest® Non-Invasive Diagnostic Approach – Michael Mueller (Switzerland)
• Endometriosis and Infertility – Exploring the Potential Role of Early Non-Invasive Diagnosis in the Patient Pathway – Gaby Moawad
• Impact on Patient Care and Quality of Life – Sarah Maheux-Lacroix
• Roundtable – How Non-Invasive Diagnosis Can Improve Care for Patients and Support Clinicians – Chairs and All
• Closing remarks – Charles Chapron & Felice Petraglia

14:15 – 15:45

• Endometriosis phenotypes and ovarian cancer – Pere N. Barri (Spain)
• Endometrial cancer, EIN and atypical hyperplasia: fertility-sparing surgery – Ursula Catena (Italy)
• Relationship between uterine fibroids, adenomyosis and uterine sarcoma – Eva Roser (Germany)
• Emerging biomarkers in uterine neoplasms – Guillaume Beinse (France)

14:15 – 15:45

• Endometriosis symptoms beyond the pelvis – Ludwig Kiesel (Germany)
• Genetic basis of comorbidity – Dora Koller (Spain)
• Immunologic basis of comorbidity – Maxime Jeljeli (USA)
• Multidimensional management of endometriosis – Felice Petraglia (Italy)

15:45 – 16:45

• Welcome & introduction – Sylvia Mechsner (Germany)
• The burden of endometriosis and a different approach to treatment – Jacques Donnez (Belgium)
• Linzagolix: from clinical trials to clinical practice (expert-led patient cases) – Marie-Madeleine Dolmans (Belgium), Sylvia Mechsner (Germany) & Mariona Rius (Spain) 
• Q&A from the audience

17:15 – 18:45

17:15 – 18:00

Debate 1 – Is endometriosis / adenomyosis a real risk for pregnancy?
Chair: Lorenza Driul (Italy)
Teresa Mira Gruber (Germany) VS Anna Peguero (Spain)

17:15 – 18:00

Debate 2 – Absolute uterine factors and desire of pregnancy: Future perspectives
Chair: Louis Marcellin (France)
Mats Brännström (Sweden) VS Tevfik Yoldemir (Türkiye)

17:15 – 18:00

• Diet, environment and endometriosis – Annemiek Nap (The Netherlands)

18:00 – 18:45

Debate 3 – Is pretreatment with GnRH a/ant needed in ART for adenomyosis?
Chair: Mariona Rius (Spain)
Sarah Maheux-Lacroix (Canada) VS Mathilde Bourdon (France)

18:00 – 18:45

Debate 4 – Isthmocele: surgery or not?
Chair: Guillaume Parpex (France)
Olarik Musigavong (Thailand) VS Michael Mueller (Switzerland)

20:00

08:30

09:00 – 10:30

• Understanding mechanisms of pain in endometriosis – Romina Nassini (Italy)
• Endometriosis clinical symptoms: impact on quality of life – Francisco Carmona (Spain)
• New ideas for endometriosis pain management – Sylvia Mechsner (Germany)
• Central sensitization evaluation and its impact on management – Stéphane Ploteau (France)

11:00 – 11:30

• Towards a worldwide strategy to fight infertility: a demographic winter – Samir Hamamah (France)

11:30 – 13:00

• How to define an Abnormal Uterine Bleeding? Silvia Vannuccini (Italy)
• Effect of AUB on reproductive health – Marie-Madeleine Dolmans (Belgium)
• AUB: evidence based on imaging process – Mathew Leonardi (Canada)
• Modern strategies for managing AUB – Mariona Rius (Spain)

13:00 – 14:00

SEUD President: Charles Chapron (France)
Congress President: Ludwig Kiesel & Sylvia Mechsner (Germany)